Sono riuscito ad individuare le esatte coordinate della gif sul mio schermo.
Dopo questo

Enum meFlags As Integer
MOUSEEVENTF_MOVE = &H1
MOUSEEVENTF_LEFTDOWN = &H2
MOUSEEVENTF_LEFTUP = &H4
MOUSEEVENTF_RIGHTDOWN = &H8
MOUSEEVENTF_RIGHTUP = &H10
MOUSEEVENTF_MIDDLEDOWN = &H20
MOUSEEVENTF_MIDDLEUP = &H40
MOUSEEVENTF_XDOWN = &H80
MOUSEEVENTF_XUP = &H100
MOUSEEVENTF_WHEEL = &H800
MOUSEEVENTF_VIRTUALDESK = &H4000
MOUSEEVENTF_ABSOLUTE = &H8000
End Enum
Declare Sub mouse_event Lib "user32" (ByVal dwFlags As meFlags, ByVal Coords As Drawing.Point, ByVal dwData As Integer, ByVal dwExtraInfo As UIntPtr)
Sub SimulateClick(ByVal Location As Drawing.Point)
Dim trect As Drawing.Rectangle = Screen.GetBounds(Location)
Dim tpnt As New Drawing.Point(65535.0 / trect.Width * Location.X, 65535.0 / trect.Height * Location.Y)
mouse_event(meFlags.MOUSEEVENTF_MOVE Or meFlags.MOUSEEVENTF_ABSOLUTE, tpnt, 0, New UIntPtr(Convert.ToUInt32(0)))
mouse_event(meFlags.MOUSEEVENTF_LEFTDOWN Or meFlags.MOUSEEVENTF_ABSOLUTE, tpnt, 0, New UIntPtr(Convert.ToUInt32(0)))
mouse_event(meFlags.MOUSEEVENTF_LEFTUP Or meFlags.MOUSEEVENTF_ABSOLUTE, tpnt, 0, New UIntPtr(Convert.ToUInt32(0)))
End Sub


Se volesse impostare le coordinate
x=911
y=733
come dovrei fare?