Non lo sai, si va per esperienza.
Certo che puoi provocare i danni, ma se usi autoruns è abbastanza difficile.
Hai un sacco di antitutto, non è una gran novità che la macchina sia lenta.
Comincerei con a togliere tutta la croppa Adobe

O4 - HKLM\..\Run: [Adobe ARM] "C:\Program Files (x86)\Common Files\Adobe\ARM\1.0\AdobeARM.exe"

Poi la croppa Asus


O4 - HKLM\..\Run: [ASUSPRP] "C:\Program Files (x86)\ASUS\APRP\APRP.EXE"
O4 - HKLM\..\Run: [ASUSWebStorage] C:\Program Files (x86)\ASUS\WebStorage Sync Agent\1.1.10.123\AsusWSPanel.exe /S
O4 - HKLM\..\Run: [SwitchBoard] C:\Program Files (x86)\Common Files\Adobe\SwitchBoard\SwitchBoard.exe


Non so perchè hai Panda con esecuzione una tantum, boh


O11 - Options group: [ACCELERATED_GRAPHICS] Accelerated graphics
O17 - HKLM\System\CCS\Services\Tcpip\..\{892BA110-5027-4C79-92EB-ECDAAC27E435}: NameServer = 8.8.8.8,8.8.4.4

Via windows live e la gallery

O18 - Protocol: wlpg - {E43EF6CD-A37A-4A9B-9E6F-83F89B8E6324} - C:\Program Files (x86)\Windows Live\Photo Gallery\AlbumDownloadProtocolHandler.dll

via
O23 - Service: Advanced SystemCare Service 8 (AdvancedSystemCareService8) - IObit - C:\Program Files (x86)\IObit\Advanced SystemCare 8\ASCService.exe
O23 - Service: @%SystemRoot%\system32\Alg.exe,-112 (ALG) - Unknown owner - C:\WINDOWS\System32\alg.exe (file missing)
O23 - Service: ASLDR Service (ASLDRService) - ASUSTek Computer Inc. - C:\Program Files (x86)\ASUS\ATK Package\ATK Hotkey\ASLDRSrv.exe
O23 - Service: ASUS InstantOn Service (ASUS InstantOn) - ASUS - C:\Program Files (x86)\ASUS\ASUS InstantOn\InsOnSrv.exe
O23 - Service: AtherosSvc - Qualcomm Atheros Commnucations - C:\Program Files (x86)\Bluetooth Suite\adminservice.exe
O23 - Service: ATKGFNEX Service (ATKGFNEXSrv) - ASUS - C:\Program Files (x86)\ASUS\ATK Package\ATKGFNEX\GFNEXSrv.exe

via roba intel
O23 - Service: Intel(R) Content Protection HECI Service (cphs) - Intel Corporation - C:\WINDOWS\SysWow64\IntelCpHeciSvc.exe
O23 - Service: @oem17.inf,%WIN32_DPTF_PARTICIPANT_PROC_SERVICE_DI SPLAY_NAME%;Intel(R) Dynamic Platform and Thermal Framework Processor Participant Service Application (DptfParticipantProcessorService) - Unknown owner - C:\WINDOWS\system32\DptfParticipantProcessorServic e.exe (file missing)
O23 - Service: @oem17.inf,%WIN32_DPTF_POLICY_CONFIGTDP_SERVICE_DI SPLAY_NAME%;Intel(R) Dynamic Platform and Thermal Framework Config TDP Service Application (DptfPolicyConfigTDPService) - Unknown owner - C:\WINDOWS\system32\DptfPolicyConfigTDPService.exe (file missing)
O23 - Service: @oem17.inf,%WIN32_DPTF_POLICY_CRITICAL_SERVICE_DIS PLAY_NAME%;Intel(R) Dynamic Platform and Thermal Framework Critical Service Application (DptfPolicyCriticalService) - Unknown owner - C:\WINDOWS\system32\DptfPolicyCriticalService.exe (file missing)
O23 - Service: @oem17.inf,%WIN32_DPTF_POLICY_LPM_SERVICE_DISPLAY_ NAME%;Intel(R) Dynamic Platform and Thermal Framework Low Power Mode Service Application (DptfPolicyLpmService) - Unknown owner - C:\WINDOWS\system32\DptfPolicyLpmService.exe (file missing)
O23 - Service: @%SystemRoot%\system32\efssvc.dll,-100 (EFS) - Unknown owner - C:\WINDOWS\System32\lsass.exe (file missing)

via croppa epson
O23 - Service: EpsonBidirectionalService - SEIKO EPSON CORPORATION - C:\Program Files (x86)\Common Files\EPSON\EBAPI\eEBSVC.exe
O23 - Service: Epson Scanner Service (EpsonScanSvc) - Unknown owner - C:\WINDOWS\system32\EscSvc64.exe (file missing)
O23 - Service: @%systemroot%\system32\fxsresm.dll,-118 (Fax) - Unknown owner - C:\WINDOWS\system32\fxssvc.exe (file missing)

via il google update (devi far fuori anche il servizio)
O23 - Service: Servizio Google Update (gupdate) (gupdate) - Google Inc. - C:\Program Files (x86)\Google\Update\GoogleUpdate.exe
O23 - Service: Servizio Google Update (gupdatem) (gupdatem) - Google Inc. - C:\Program Files (x86)\Google\Update\GoogleUpdate.exe

Via questa roba strana

O23 - Service: @%SystemRoot%\system32\ieetwcollectorres.dll,-1000 (IEEtwCollectorService) - Unknown owner - C:\WINDOWS\system32\IEEtwCollector.exe (file missing)
O23 - Service: Intel(R) Capability Licensing Service Interface - Intel(R) Corporation - C:\Program Files\Intel\iCLS Client\HeciServer.exe
O23 - Service: Intel(R) ME Service - Intel Corporation - C:\Program Files (x86)\Intel\Intel(R) Management Engine Components\FWService\IntelMeFWService.exe
O23 - Service: Intel(R) Dynamic Application Loader Host Interface Service (jhi_service) - Intel Corporation - C:\Program Files (x86)\Intel\Intel(R) Management Engine Components\DAL\jhi_service.exe
O23 - Service: @keyiso.dll,-100 (KeyIso) - Unknown owner - C:\WINDOWS\system32\lsass.exe (file missing)
O23 - Service: LiveUpdate (LiveUpdateSvc) - IObit - C:\Program Files (x86)\IObit\LiveUpdate\LiveUpdate.exe
O23 - Service: Intel(R) Management and Security Application Local Management Service (LMS) - Intel Corporation - C:\Program Files (x86)\Intel\Intel(R) Management Engine Components\LMS\LMS.exe

Via lo scheduler malware ed il relativo servizio

O23 - Service: MBAMScheduler - Malwarebytes Corporation - C:\Program Files (x86)\Malwarebytes Anti-Malware\mbamscheduler.exe
O23 - Service: MBAMService - Malwarebytes Corporation - C:\Program Files (x86)\Malwarebytes Anti-Malware\mbamservice.exe
O23 - Service: @comres.dll,-2797 (MSDTC) - Unknown owner - C:\WINDOWS\System32\msdtc.exe (file missing)
O23 - Service: Panda Protection Service (NanoServiceMain) - Panda Security, S.L. - C:\Program Files (x86)\Panda Security\Panda Cloud Antivirus\PSANHost.exe

Via la croppa NVIDIA
O23 - Service: NVIDIA Display Driver Service (nvsvc) - Unknown owner - C:\WINDOWS\system32\nvvsvc.exe (file missing)
O23 - Service: NVIDIA Update Service Daemon (nvUpdatusService) - NVIDIA Corporation - C:\Program Files (x86)\NVIDIA Corporation\NVIDIA Update Core\daemonu.exe
O23 - Service: Origin Client Service - Electronic Arts - C:\Program Files (x86)\Origin\OriginClientService.exe
O23 - Service: Panda Devices Agent (PandaAgent) - Panda Security, S.L. - C:\Program Files (x86)\Panda Security\Panda Devices Agent\AgentSvc.exe
O23 - Service: Panda Product Service (PSUAService) - Panda Security, S.L. - C:\Program Files (x86)\Panda Security\Panda Cloud Antivirus\PSUAService.exe
O23 - Service: @%systemroot%\system32\Locator.exe,-2 (RpcLocator) - Unknown owner - C:\WINDOWS\system32\locator.exe (file missing)
O23 - Service: @%SystemRoot%\system32\samsrv.dll,-1 (SamSs) - Unknown owner - C:\WINDOWS\system32\lsass.exe (file missing)
O23 - Service: Skype Updater (SkypeUpdate) - Skype Technologies - C:\Program Files (x86)\Skype\Updater\Updater.exe
O23 - Service: @%systemroot%\system32\spoolsv.exe,-1 (Spooler) - Unknown owner - C:\WINDOWS\System32\spoolsv.exe (file missing)
O23 - Service: @%SystemRoot%\system32\sppsvc.exe,-101 (sppsvc) - Unknown owner - C:\WINDOWS\system32\sppsvc.exe (file missing)
O23 - Service: StartMenu8 Service (StartMenuService) - IObit - C:\Program Files (x86)\IObit\Start Menu 8\StartMenuServices.exe

Via steam (no giochi)

O23 - Service: Steam Client Service - Valve Corporation - C:\Program Files (x86)\Common Files\Steam\SteamService.exe
O23 - Service: SwitchBoard - Adobe Systems Incorporated - C:\Program Files (x86)\Common Files\Adobe\SwitchBoard\SwitchBoard.exe
O23 - Service: TeamViewer 10 (TeamViewer) - TeamViewer GmbH - C:\Program Files (x86)\TeamViewer\TeamViewer_Service.exe
O23 - Service: @%SystemRoot%\system32\ui0detect.exe,-101 (UI0Detect) - Unknown owner - C:\WINDOWS\system32\UI0Detect.exe (file missing)
O23 - Service: Intel(R) Management and Security Application User Notification Service (UNS) - Intel Corporation - C:\Program Files (x86)\Intel\Intel(R) Management Engine Components\UNS\UNS.exe
O23 - Service: @%SystemRoot%\system32\vaultsvc.dll,-1003 (VaultSvc) - Unknown owner - C:\WINDOWS\system32\lsass.exe (file missing)
O23 - Service: @%SystemRoot%\system32\vds.exe,-100 (vds) - Unknown owner - C:\WINDOWS\System32\vds.exe (file missing)
O23 - Service: @%systemroot%\system32\vssvc.exe,-102 (VSS) - Unknown owner - C:\WINDOWS\system32\vssvc.exe (file missing)
O23 - Service: @%systemroot%\system32\wbengine.exe,-104 (wbengine) - Unknown owner - C:\WINDOWS\system32\wbengine.exe (file missing)
O23 - Service: @%ProgramFiles%\Windows Defender\MpAsDesc.dll,-320 (WdNisSvc) - Unknown owner - C:\Program Files (x86)\Windows Defender\NisSrv.exe (file missing)
O23 - Service: @%ProgramFiles%\Windows Defender\MpAsDesc.dll,-310 (WinDefend) - Unknown owner - C:\Program Files (x86)\Windows Defender\MsMpEng.exe (file missing)
O23 - Service: @%Systemroot%\system32\wbem\wmiapsrv.exe,-110 (wmiApSrv) - Unknown owner - C:\WINDOWS\system32\wbem\WmiApSrv.exe (file missing)
O23 - Service: @%PROGRAMFILES%\Windows Media Player\wmpnetwk.exe,-101 (WMPNetworkSvc) - Unknown owner - C:\Program Files (x86)\Windows Media Player\wmpnetwk.exe (file missing)
O23 - Service: Wacom Professional Service (WTabletServicePro) - Wacom Technology, Corp. - C:\Program Files\Tablet\Wacom\WTabletServicePro.exe
O23 - Service: ZAtheros Bt and Wlan Coex Agent - Atheros - C:\Program Files (x86)\Bluetooth Suite\Ath_CoexAgent.exe


Insomma togli tutto quello che non ti è indispensabile.
Poi passa ai servizi e fai la stessa cosa