Direi di eliminare
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = http://www.pxwptbtfxodolqljmgcvgn.n...ifVs6OnfrTD.jpg

O2 - BHO: (no name) - {F5C99AE5-9BDF-6D9A-9A73-39F3356B4A99} - C:\PROGRA~1\GLOBAL~1\READMEFORK.exe